Senior Manager/Manager, Clinical Supply Chain CMO Site Management

About us

BeOne is a global oncology company that is discovering and developing innovative treatments that are more affordable and accessible to cancer patients worldwide. With a broad portfolio, we are expediting development of our diverse pipeline of novel therapeutics through our internal capabilities and collaborations. We are committed to radically improving access to medicines for far more patients who need them. Our growing global team of more than 10,000 colleagues spans five continents, with administrative offices in Basel, Beijing, and Cambridge, U.S. To learn more about BeOne, please visit www.beonemedicines.com and follow us on LinkedIn and X (formerly known as Twitter).

BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer.

Job Description:

General Description:

Contract Manufacturing Site Managers work closely with contract manufacturers (CMOs) worldwide, Supply Chain leads, Quality and operations partners to ensure supply continuity with optimal cost and quality. Contract Manufacturing Site Managers also provide oversight of the production plans that will help drive the evolution and implementation of new platforms, systems and processes that enable greater operational efficiency, accuracy and utilization of the clinical product pipeline. In this role you will use your manufacturing experience and partnerships to optimize the overall supply chain to help to achieve the goal of delivering BeOne’s pipeline to patients.

Essential Functions of the Job:

• Serve as the Sr. Contract Manufacturing Site Manager overseeing BeOne’s global network (with specific focus on APAC) of clinical contract manufacturing organizations (CMOs) supporting clinical drug labeling and packaging. Scope of work includes management of drug from the release of Drug Product (DP) at the filling site through release of Final Packaged Goods (FG) at the label/pack site; scheduling and oversight of label/pack execution activities at the label/pack site; and ensuring the necessary DP materials and FG components are available for execution.
• Interact with senior internal and external leadership on significant issues and business meetings and relationships
• Participate in cross-functional teams in evaluating and selecting CMOs for a particular project as requested.
• Provide input to the internal CMO/partner SPOC ensuring that the overall relationship between BeOne and the CMO/partner is healthy.
• Drive continuous improvement of the business relationship.
• Participate in CMO Site visits as requested.
• Proactively managing the operational pack activities (schedule, timelines, etc.) of the CMO ensuring program cost, quality, metrics, delivery and technology objectives are met as well as managing the partner performance to achieve them. Proactively intercede if goals and timelines are jeopardized, communicating to appropriate stakeholders as needed.
• Identify any supply constraints and negotiate/resolve with the CMO any issues to meet the supply plan.
• Partner with key stakeholders in the preparation for Requests for Quotes (RFQs), Statements of Work (SOW) and negotiating supply agreements for clinical programs. 
• Serve as the manufacturing outsourcing team leader on cross-functional teams as requested in support of clinical finished good packaging.
• Generate and distribute reports for overall site metrics, key issues, production status and highlights, and regular operational performance summary updates as required.
• Participate in Master Service Agreement creation and maintenance as requested so that it accurately reflects the existing business relationship.
• Support Global QA in establishing QA agreements with all CMOs and assuring that Product Specific Requirements (PSRs) are established before projects are initiated. 
• Work independently, developing and leading process improvements for a variety of complex and advanced technical problems and initiatives for self as well as for department. 
• Apply advanced technical expertise in solving and developing department initiatives and goals. 
• Periodically report on performance and operations at internal and/or external Operations Reviews. 
• Set personal performance goals and provide input to departmental objectives.
• Establish work priorities to meet targets and timelines.
• Collaborate and author department policies and procedures.
• Make decisions that impact the goals and objectives of the department.
• Notify Management of potential business issues that may affect project timelines.

Supervisory Responsibilities:  

• None

Qualification Required:

Education Required:

Bachelor’s or master’s degree in science or business administration, Operations Management, or similar education required, Supply Chain Management, and/or Management of Science or equivalent filed is preferred.

Computer Skills:   

• Efficient in Microsoft Word, Excel, Project, PowerPoint and Outlook.
• Experience with an ERP system (SAP preferred).

Other Qualifications:    

• Understands comprehensive global pharmaceutical regulatory requirements (e.g. cGMP, GDP, and/or GCP).
• APICS certification a plus.
• Due to the global nature of the company, early morning or evening meetings may be required.
• Experience in vendor oversight and managing external partnerships and relations.
• Familiarity with risk management tools (FMEA, etc.).
• Demonstrated financial skills (i.e. developing and managing a budget, etc.)

Travel: ~15%, domestic and international

What We Offer To Our Valued Employees

• Market competitive compensation package including performance-based annual bonus scheme

• Company shares (generous welcome grant!)

• In-house and external learning and development opportunities

• Fantastic benefits program and keep improving!

• Plus you get to work with a dynamic team of collaborative, supportive, inclusive, and fun professionals whose mission is clear: Cancer has no borders and neither do we.

• Join us and Make momentum in your career!

BeOne Global Competencies

When we exhibit our values of Patients First, Collaborative Spirit, Bold Ingenuity and Driving Excellence, through our twelve global competencies below, we help get more affordable medicines to more patients around the world.

• Fosters Teamwork
• Provides and Solicits Honest and Actionable Feedback
• Self-Awareness
• Acts Inclusively
• Demonstrates Initiative
• Entrepreneurial Mindset
• Continuous Learning
• Embraces Change
• Results-Oriented
• Analytical Thinking/Data Analysis
• Financial Excellence
• Communicates with Clarity

BeOne is committed to respect and protect personal information rights of job applicants and will process job applicants’ personal information in accordance with applicable laws and regulations.

Due to BeOne’s global operation, job applicants’ data will be stored overseas with adequate protection. Besides, job applicants’ data will be stored for no longer than is necessary to facilitate potential application for other suitable positions in BeOne. For further details, please refer to BeOne’s Job Applicant Privacy Policy (https://beonemedicines.com/privacy-policy).

If you voluntarily provide your personal information to us, it is deemed as you have acknowledged and consented to (if required by the applicable laws) BeOne’s Job Applicant Privacy Policy as well as the relevant privacy terms. If you voluntarily provide the personal information of other job applicants to us, it is deemed as you have ensured that the relevant individuals have acknowledged and consented to (if required by the applicable laws) BeOne’s Job Applicant Privacy Policy as well as the relevant privacy terms.

If you have any concern, please DO NOT provide any resume or other personal information to us.