Senior Principal Scientist, Lab Head, Synthetic Immunity

The Opportunity

The Department of Research Oncology at Genentech is excited to announce an  opportunity for a Senior Principal Scientist, Lab Head, to join the Synthetic  Immunity division encompassing immune engager and CAR-T cell therapy  programs. The position will lead a research group focused on developing next  generation programs to advance Genentech’s Synthetic Immunity efforts. 

The ideal candidate will have a deep background in T cell immunology and/or  cancer immunology. Extensive experience working with T cells in both in vitro  and in vivo models is required. Deep knowledge of cellular immunology is  strongly preferred. 

The successful candidate will lead a highly productive research team and  integrate efforts across cross-functional teams to identify new targets and  therapeutic hypotheses, and to advance transformative medicines using  Synthetic Immunity approaches. Strong collaborative and excellent  communication skills are essential. 

Key responsibilities include: 

• Research Leadership: Lead and manage a high-performing team in the discovery  and advancement of novel programs in Synthetic Immunity. 
• Translational Impact: Generate high-quality, original research that advances our  understanding of T cell biology and tumor immunology to contribute to the  development of next generation Synthetic Immunity approaches. 
• Communication and Collaboration: Work effectively in cross-functional teams by  collaborating closely with colleagues from other Research departments, Drug  Development, Translational Medicine and Early Clinical Development. 

Who You Are  

• Educational Background: Ph.D. in Immunology, Cell Biology or other related field
• Experience: Postdoctoral training and a minimum of 5 years of industry  experience required. Your record should reflect high-impact publications, patents,  and successful project transitions. 
• Demonstrated expertise in T cell immunology, cellular immunology, and/or  cancer immunology. 
• Leadership and Collaboration: Exceptional leadership abilities with a proven track  record of working with multidisciplinary teams, excellent written and verbal 
• Communication skills, and a collaborative spirit to work closely with cross functional research teams. 

Preferred 

• Experience working with human and/or mouse T cells. 
• Experience with engineering human T cells. 
• Experience with syngeneic and/or xenograft in vivo models 
• Experience with deep profiling of T and other immune cells (e.g. multiparameter  flow, molecular profiling, etc.) 

If you are passionate about harnessing the power of the immune system and  Synthetic Immunity approaches to uncover and develop novel therapies for  cancer, we encourage you to apply.  

Relocation benefits are available for this posting.

The expected salary range for this position based on the primary location of California is $165,200 to $306,000. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

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Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

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