Senior Staff PLM Strategy

What if the work you did every day could impact the lives of people you know? Or all of humanity?

At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.

Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.

Job Summary

The Senior Staff, PLM Strategy (P05) is responsible for enabling, advancing, and governing the enterprise Product Lifecycle Management (PLM) strategy, operating model, and transformation roadmap. This role partners with business, functional, and technology leaders to align PLM capabilities with enterprise objectives, enabling scalable business growth, operational excellence, digital transformation, and data-driven decision-making.

The position serves as a recognized enterprise thought role, driving future-state PLM capabilities, business process architecture, solution strategy, data governance, and organizational change. Operating with a high degree of autonomy and influence, the role translates long-term business priorities into strategic PLM investments and transformational initiatives that deliver measurable business outcomes. The role acts as a key link between executive vision, business capabilities, technology strategy, operational execution, R&D formulation requirements, master data architecture, and solution/data architecture decisions.

Key Responsibilities

• Evolve and champion the enterprise PLM vision, operating model, capability strategy, and multi-year transformation roadmap aligned with business priorities and growth objectives.
• Lead business process architecture and value stream transformation, driving standardization, simplification, and future-state operating models.
• Evolve enterprise PLM architecture, champion data governance, and capability frameworks that enable scalable Product lifecycle management across business functions, ensuring alignment between business capabilities, digital platforms, and enterprise data management.
• Partner with R&D, Supply Chain, Quality and Manufacturing stakeholders to understand formulation BoM lifecycle updates, translate formulation changes into PLM requirements, and clarify the intended business, compliance, data, and operational outcomes of each change.
• Collaborate across PLM, R&D, MDM, Quality, Manufacturing, IT, Solution Architecture, and Data Architecture teams to align change intent, impact assessment, data readiness, and implementation outcomes.
• Develop and govern integrated PLM and MDM roadmaps, aligning master data strategy, information architecture, data governance, solution architecture, and digital platform capabilities with enterprise priorities.
• Drive digital transformation and innovation by evaluating, championing, and responsibly adopting AI/LLM capabilities, automation, advanced analytics, process mining, and emerging technologies to improve business value, operational effectiveness, and user experience across the PLM ecosystem.
• Establish governance and portfolio management frameworks to prioritize investments, manage risks, and maximize business value realization.
• Influence executive decision-making and investment prioritization through strategic planning, business cases, and value realization frameworks to influence strategic decisions and align PLM initiatives with enterprise objectives.
• Provide thought leadership and organizational capability development by mentoring teams and promoting best practices in PLM strategy and transformation.
• Measure and communicate business value realization, defining strategic KPIs, capability maturity metrics, and transformation outcomes.

Required Qualifications

• Bachelor’s or master’s degree in engineering, Life Sciences, Information Systems, Business, Operations, or a related discipline.
• Typically, 10–15 years of progressive experience in PLM, enterprise architecture, business transformation, digital strategy, product lifecycle management, Master Data Management (MDM), solution architecture, data architecture, or R&D/product formulation environments.

Demonstrated expertise in:

• PLM & MDM Strategy, Governance, and Roadmap Development
• Business Architecture & Value Stream Transformation
• Item and BoM Lifecycle, Requirements Translation & Change Impact Analysis
• Solution Architecture, Data Architecture & Information Governance
• Master Data Management, Data Quality & Enterprise Information Architecture
• Portfolio, Program & Transformation Leadership
• Organizational Change Management & Business Adoption
• Executive Influence, Strategic Thinking & Enterprise Leadership

Preferred Qualifications

• Industry experience in MedTech, Life Sciences, Pharma, Healthcare, or Manufacturing
• Expertise in PLM platforms and digital transformation technologies - Siemens Teamcenter, SAP PLM, SAP S/4, Agile PLM, or equivalent ecosystems.
• Experience with R&D collaboration, requirements translation, and change management
• Proven ability to develop PLM & MDM strategies, roadmaps, and governance frameworks
• Knowledge of Solution Architecture, Data Architecture, and Enterprise Information Management
• Familiarity with AI/LLM, analytics, automation, and data-driven operating models
• Experience in enterprise transformation, process optimization, and capability for maturity development
• Advanced degree preferred (MBA, Engineering, Technology, or related field)

We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact [email protected]. To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf. The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants. This role is not eligible for visa sponsorship.