Director, US Marketing, NF1 PN

Are you ready to define how healthcare professionals recognize and treat plexiform neurofibromas in neurofibromatosis type 1?

As Director of HCP Marketing for NF1 PN, you will lead the strategy that helps clinicians identify appropriate patients and confidently use Koselugo, a MEK 1/2 inhibitor approved in 2020, to change lives in a rare, underserved condition. Your work will translate insight into action, elevating standards of care and ensuring more patients receive the benefit of a proven therapy.

Based in Boston, you will join a close-knit, mission-driven team that partners seamlessly across Sales, Medical, Regulatory, Patient Services, and Analytics. You will shape the national HCP engagement plan, coach others to raise the bar, and deliver measurable growth while maintaining the highest ethical standards. Can you turn data and KOL perspectives into bold, compliant tactics that shift clinical behavior for the right patients?

Accountabilities:

• Brand Strategy Leadership: Own the HCP strategy for the NF1 PN US business, creating a clear plan that differentiates Koselugo and guides field and non-personal promotion to drive appropriate use.

• Customer Insight Generation: Build a deep, nuanced understanding of HCP and patient needs through research, advisory boards, and sustained KOL engagement; translate findings into targeted, testable tactics.

• Performance Management: Establish critical metrics for personal and non-personal channels, track progress weekly and monthly, and adjust programs to improve reach, quality of engagement, and treatment adoption.

• Cross-Functional Leadership: Partner closely with Sales, Training, Medical, Regulatory, Legal, Compliance, Patient Services, and the Promotional Review Committee to align strategy, accelerate execution, and ensure all materials meet the highest standards.

• People Leadership: Serve as day-to-day manager for the Associate Director of HCP Marketing (dotted line), providing clear priorities, coaching, and feedback to elevate team performance.

• Media Strategy and Measurement: Lead strategic oversight of the HCP media plan; optimize channel mix, creative rotation, and spend based on impact, efficiency, and brand objectives.

• Analytics Partnership: Collaborate with commercial analytics and insights teams to assess market dynamics, identify opportunity segments, quantify barriers, and design primary and secondary research that sharpens targeting and messaging.

• Annual Planning and Budgeting: Drive annual brand planning, connecting short- and long-term priorities to a resourced tactical plan and budget that deliver sustainable, compliant growth.

• Executive Communication: Build streamlined, persuasive updates for senior commercial and medical leadership through monthly business reviews and quarterly reviews; highlight learnings, decisions, and next steps.

• Agency and Resource Management: Direct the brand agency of record and other partners, ensuring on-brief delivery, speed, and value; manage budgets with rigor and transparency.

• Ethics and Compliance: Uphold the company’s Code of Ethics and Business Conduct in all activities; ensure promotional materials and tactics are evidence-based, accurate, and appropriate for HCP audiences.

Essential Skills/Experience:

• Bachelor's degree

• 10+ years of professional experience; prefer marketing, sales, agency, or health care experience

• Track record of developing and implementing marketing strategies and tactics that have delivered strong commercial results in competitive environments

• Proven leadership skills and the ability to collaborate in a matrix environment

• Track record that demonstrates the ability to build high performing teams and support individuals in their professional development

• Strong ability to manage multiple projects across functional areas, and work independently when appropriate, in teams and as a sub-team lead

• The duties of this role are generally conducted in an office environment. As is typical of an office-based role, employees must be able, with or without an accommodation to: use a computer; engage in communications via phone, video, and electronic messaging; problem solve; engage in complex and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours

Desirable Skills/Experience:

• Advanced degree, MBA

• Strong scientific orientation and background

• Rare disease/high-value biologics experience

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Why AstraZeneca:

At AstraZeneca, you will work at the intersection of science, compassion, and execution, where proximity to patients and clinicians keeps purpose tangible and urgent. We combine the agility of a biotech mindset with the scale and discipline of a global leader, bringing diverse experts together to solve problems that truly matter. You will have the autonomy to try new approaches, the data and technology to test and learn quickly, and the support of leaders who value kindness alongside ambition. Your marketing craft will directly influence care pathways for people with rare conditions—turning insight into action, and action into better futures.

Call to Action:

If you are ready to build a category-defining HCP strategy that elevates care for NF1 PN and delivers measurable impact for patients and the business, step forward and introduce yourself today.

The annual base pay for this position ranges from US $194,126 & $291,189. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans. 

Date Posted

24-Jul-2026

Closing Date

12-Aug-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.