Clinical Research Manager (CRM) Lead

Job Description

An amazing opportunity has arisen for a Clinical Research Manager (CRM) Lead.

We aspire to be the premier research-intensive biopharmaceutical company. We're at the forefront of research to deliver innovative health solutions that advance the prevention and treatment of diseases around the world.

Join us in our mission to use the power of leading-edge science to save and improve lives.

Responsibilities

• Lead and oversee a portfolio of clinical trials across one or more Therapeutic Areas, ensuring successful delivery from feasibility through study close-out.

• Drive study performance by ensuring enrollment, quality, timelines, milestones, and compliance with ICH-GCP, local regulations, and our standards.  

• Develop and implement operational strategies, quality plans, and risk mitigation approaches to ensure optimal execution of the clinical trial portfolio.

• Lead, coach, and develop a team of Clinical Research Managers, fostering high performance, talent development, succession planning, and employee engagement.

• Build strong partnerships with internal cross-functional stakeholders and external collaborators, including investigators, sites, vendors, and regulatory authorities.

• Contribute to country and global strategic initiatives, supporting the growth of clinical research capabilities and the successful delivery of the development pipeline.

Skills & Experience

• Extensive experience in clinical research operations, including clinical trial management, project leadership, and team management.  

• Strong knowledge of ICH-GCP, regulatory requirements, clinical trial processes, and the local clinical research environment.  

• Demonstrated leadership capabilities with experience developing, motivating, and managing high-performing teams.

• Excellent project management, organizational, and problem-solving skills, with the ability to prioritize multiple complex initiatives simultaneously.

• Strong communication, collaboration, and stakeholder management skills in a global and cross-functional environment.  

• Strategic mindset with the ability to drive execution, manage change, influence stakeholders, and build long-term partnerships.

Required Skills:

Clinical Research Management, Clinical Sciences, Clinical Study Design, Decision Making, Early Clinical Development, Medical Research, Oncology Trials, People Leadership

Preferred Skills:

Current Employees apply HERE

Current Contingent Workers apply HERE

Search Firm Representatives Please Read Carefully 
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company.  No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. 

Employee Status:

Regular

Relocation:

VISA Sponsorship:

Travel Requirements:

Flexible Work Arrangements:

Hybrid

Shift:

Valid Driving License:

Hazardous Material(s):

Job Posting End Date:

08/19/2026

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