Variant Scientist III

Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Office

Job Description

As part of the Thermo Fisher Scientific team, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life every single day to enable our customers to make the world healthier, cleaner and safer. We provide our global teams with the resources needed to achieve individual career goals while helping to take science a step beyond by developing solutions for some of the world’s toughest challenges, like protecting the environment, making sure our food is safe or helping find cures for cancer.

Discover Impactful Work
The Variant Scientist III will review, analyze, and compile complex clinical data from primary literature and clinical trials specific to biomarkers in cancer. You’ll provide scientific and technical expertise to a cross-functional team of scientists and software developers to build and maintain an internal knowledgebase of genomic aberrations and therapies relevant to cancer.  This role is part of the Bioinformatics team within the Clinical Next Generation Sequencing Division. The mission of this business unit is to develop next-generation sequencing-based solutions to support oncology research and other important unmet medical needs.
 

Location

This is a fully onsite role based in Ann Arbor, MI and relocation assistance is not provided. 

A Day in the Life

• Read, interpret, and curate evidence from approved therapies, clinical guidelines, clinical trials, and scientific literature using customized software tools.
• Actively participate in the interpretation, analysis, and summarization of various clinical sources for somatic and germline variant annotations and classification.
• Review primary literature and author summaries that describe the relationships between gene variants and disease prognosis, diagnosis, and therapy selection.
• Actively provide translational and clinical oncology expertise to the curation team in solid and/or hematological cancers.
• Follow and maintain sustainable processes that ensure data accuracy and quality.
• Work in a fast pace, cross-functional team of bioinformatics scientists, variant scientists, and software engineers to define and refine clinical reports.

Keys to Success

Education

• PhD in cancer biology, cancer genomics, or molecular biology with expertise in solid or heme cancers. Post-doctoral experience preferred but not required.

Experience

• Demonstrated understanding of cancer genomics, tumor biology, oncogenic signaling pathways.
• Experience in reviewing and summarizing scientific literature for somatic and germline variants.
• Experience with cancer mutation databases and disease ontologies.
• Industry or clinical laboratory experience working in genomic variant curation and clinical interpretation is preferred.
• Experience with IVD/regulated product development or genetic counseling is a plus.

Knowledge, Skills, Abilities

• Excellent written and oral communication skills.
• Excellent organizational skills with ability to multi-task
• Ability to work independently and collaboratively.
• Positive attitude with strong interpersonal skills.

Other

• Must be able to pass a comprehensive background check and drug screen.