- Location
- Cambridge, MA · Cambridge, Massachusetts, United States
- Department
- mRNA Sciences
- Experience
- 1+ years
- Source
- Greenhouse
Description
Company Overview:
Beam Therapeutics is a biotechnology company committed to establishing the leading, fully integrated platform for precision genetic medicines. To achieve this vision, Beam has assembled a platform with integrated gene editing, delivery and internal manufacturing capabilities. Beam’s suite of gene editing technologies is anchored by base editing, a proprietary technology that is designed to enable precise, predictable and efficient single base changes, at targeted genomic sequences, without making double-stranded breaks in the DNA. This has the potential to enable a wide range of therapeutic editing strategies that Beam is using to advance a diversified portfolio of base editing programs. Beam is a values-driven organization committed to its people, cutting-edge science, and a vision of providing life-long cures to patients suffering from serious diseases.
Position Overview:
Beam is looking for a highly motivated co-op student to join our mRNA Science Team from January to June of 2027. The co-op will assist in screening different sequences of mRNA and chemical modification to enhance the quality of mRNA used across multiple programs. Specifically, this role will involve performing and optimizing in vitro transcription (IVT) reactions and running biochemical assays to characterize the mRNA products. The ideal candidate for this role is detail-oriented, persistent, highly organized, and has an innovative mindset toward solving technical challenges. This position will play a central role in advancing our core mRNA technology, while providing the individual exposure to one of the most important classes of medication of the 21st century.
Responsibilities:
- Generate desired clones through molecular cloning, followed by DNA amplification and purification.
- Produce mRNA with novel sequences and chemistry by IVT reactions.
- Analyze the product by capillary electrophoresis, protein expression, and HPLC chromatography.
- Test mRNA expression in mammalian cell line.
- Work collaboratively with other teams to perform editing experiments in cells.
- Maintain detailed documentation of experiments in the ELN system.
- Adhere to all laboratory safety requirements and procedures.
Qualifications:
- Pursuing a BS or MS in biological sciences or a related field (Bioengineering, Biochemistry/Biophysics, Cell Biology/Molecular Biology) with at least 1 year of relevant hands-on laboratory experience.
- Knowledge of biochemical & molecular biology methods used in drug discovery and development.
- Proficient in Excel, PowerPoint, and data analysis.
- Experience maintaining a lab notebook and following written protocols.
- Highly motivated to learn, with a collaborative mindset, strong attention to detail, and excellent organizational and communication skills.
- Applicants must be currently enrolled in a degree-granting college or university program and maintain their student status throughout the duration of the co-op to be eligible.
Hourly pay will will be determined based on several factors, including but not limited to, relevant experience, skills, and education.