FSP - Scientist - Lead Generation Biology

Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Laboratory Setting, Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.)

Job Description

This is a fully onsite role based at our customer’s site in San Diego, CA (Carmel Valley) We welcome applicants from all locations within the US. Please note that relocation assistance is not provided for this position, and any relocation costs will be the responsibility of the candidate.  

Must be legally authorized to work in the United States without sponsorship. 

Must be able to pass a comprehensive background check, which includes a drug screening. 

At Thermo Fisher Scientific, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life - enabling our customers to make the world healthier, cleaner and safer. We provide our teams with the resources needed to achieve individual career goals while taking science a step beyond through research, development and delivery of life-changing therapies. With clinical trials conducted in 100+ countries and ongoing development of novel frameworks for clinical research through our PPD clinical research portfolio, our work spans laboratory, digital and decentralized clinical trial services. Your determination to deliver quality and accuracy will improve health outcomes that people and communities depend on – now and in the future.

Thermo Fisher's clinical research business is a leading global contract research organization and world leader in serving science. We are passionate, deliberate, and driven by our mission – to enable our customers to make the world healthier, safer, and cleaner.

Our Laboratories Functional Service Partnership (FSP) team plays a direct role in advancing drug development by creating sustained groups of talent within our customers’ organizations to provide long-term support. Through this collaborative approach, our professionals bring their commitment to excellence, industry knowledge, and operational strength directly into customer environments, helping to enhance capabilities and advance the delivery of life-changing therapies.

We are seeking a highly motivated and collaborative Scientist to join the In Vitro Pharmacology team at our client site. This individual will be primarily responsible for optimizing and executing weekly in vitro pharmacology assays in support of lead optimization campaigns in the context of multidisciplinary teams. The role will involve critical analysis of assay data to guide the identification and optimization of lead compounds, alongside thorough documentation and presentation of results. Our collaborative, fast-paced work environment emphasizes efficiency and continuous improvement.

Key responsibilities:

• Perform routine assays to support lead identification campaigns
• Optimize and conduct functional and binding assays to support profiling of molecules and mechanism of action studies
• Develop clear understanding of assay mechanisms and workflow logistics
• Assist with generating and maintaining cell lines and perform assays for their characterization
• Rapidly learn and implement new assays and analysis methods
• Track and document assay performance
• Assist with process improvements to enhance efficiency and research quality
• Effectively multitask and advance various projects simultaneously without compromising data quality or reproducibility
• Work independently as well as in a team environment toward timely execution of shared team deliverables

Education and Experience:

• Bachelor's degree in lab sciences such as Chemistry, Biochemistry, Material Science, Immunology, Biology, Molecular Biology or similar
• Scientist: Previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 2+ years’)
• OR Masters degree

In some cases, an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.

Knowledge, Skills and Abilities:

• Collaborative and highly motivated
• Hands-on experience conducting in vitro assays for diverse pharmacological targets, such as SLC transporters, GPCRs, ion channels, and kinases
• Experience with radioligand binding assays preferred
• Expertise in molecular pharmacology and/or chemical biology preferred
• Experience and knowledge of mammalian cell culture and aseptic techniques
• Outstanding experimental design, problem-solving, and data analysis skills
• Ability to meet deadlines
• Experience using laboratory automation, inventory systems, data analysis (curve fitting, determination of potency, affinity, efficacy) and informatics systems
• Enthusiasm for developing and expanding technical and theoretical knowledge base
• Working knowledge of Excel, GraphPad Prism and Spotfire software helpful
• Working knowledge of LIMS systems preferred
• Excellent communication (written and verbal), time management, organizational and interpersonal skills to ensure operational excellence of daily laboratory needs
• Embody the client’s core values of Passion, Collaboration, Tenacity, Innovation, and Integrity

Working Environment:

Below is listed the working environment/requirements for this role:

Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner.

Able to work upright and stationary and/or standing for typical working hours.

Able to lift and move objects up to 25 pounds

Able to work in non-traditional work environments.

Able to use and learn standard office equipment and technology with

proficiency.

May have exposure to potentially hazardous elements, including infectious agents, typically found in healthcare or laboratory environments.

Able to perform successfully under pressure while prioritizing and handling multiple projects or activities.

Benefits

We offer competitive remuneration, annual incentive plan bonus, healthcare, and a range of employee benefits. Thermo Fisher Scientific offers employment with an innovative, forward-thinking organization, and outstanding career and development prospects. We offer an exciting company culture that stands for integrity, intensity, involvement, and innovation!

Compensation and Benefits

The hourly pay range estimated for this position based in California is $31.00–$38.50.

This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:

• A choice of national medical and dental plans, and a national vision plan, including health incentive programs

• Employee assistance and family support programs, including commuter benefits and tuition reimbursement

• At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy

• Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan

• Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount

For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards