Global Study Manager

Are you ready to lead global clinical studies that move life-changing medicines to patients faster? In this role, you will orchestrate complex, multi-country trials from protocol development through close-out and archiving, aligning cross-functional experts and external partners to deliver to time, cost and quality.

You will be a key member of a high-calibre global study team, providing day-to-day leadership and oversight of delegated study activities. How will you bring clarity and pace across vendors, sites, and internal specialists to keep studies inspection-ready and on track for decisive readouts?

Accountabilities:

• Study Delivery Oversight: Partner with internal experts and external service providers to ensure on-time, on-budget, high-quality execution of delegated study components across geographies.

• Study Documentation Leadership: Lead or contribute to the development and review of delegated study documents, including Informed Consent Forms, master Clinical Study Agreements, vendor specifications and study-specific procedures.

• CRO and Vendor Management: Maintain effective relationships and provide robust oversight of CRO project managers and other providers, ensuring clear expectations, documented oversight and delivery to agreed timelines, budgets and quality standards.

• Operational Communication: Plan and run critical internal and external meetings such as investigators’ and monitors’ meetings, driving alignment on goals, timelines and risk mitigations.

• Supply and Materials Coordination: Liaise with Clinical Supply Chain and external partners to secure uninterrupted supply of investigational product and study materials.

• Risk and Issue Management: Proactively identify risks and issues; develop and execute mitigation and action plans to protect patient safety, data integrity and study timelines.

• Inspection Readiness and TMF Quality: Ensure delegated study documents are complete, accurate and quality-checked in the Trial Master File, maintaining inspection readiness at all times.

• Financial Stewardship: Support budget activities for delegated scope, including external service provider invoice reconciliation and variance tracking.

• Process Excellence and Compliance: Adhere to global processes, SOPs, policies and ICH GCP, championing best practices and contributing to continuous process improvement.

• Project Management Support: Support the Global Study Director and/or Global Study Associate Director per agreed delegation, providing planning, tracking and reporting that enable confident decision-making.

• Improvement Projects: Take on non-drug project assignments to improve ways of working, lead targeted process improvements and share learnings across teams to elevate performance.

Essential Skills/Experience:

• University degree (or equivalent), preferably in medical or biological sciences or discipline associated with clinical research.

• Relevant experience from within the pharmaceutical industry or similar organization or academic experience, preferably of at least 3 years.

• Knowledge of clinical development / drug development process in various phases of development and therapy areas

• Excellent knowledge of international guidelines ICH/GCP

• Excellent communication and relationship building skills, including external service provider management skills

• Good project management skills

• Demonstrated ability to collaborate as well as work independently • Demonstrated leadership skills

• Computer proficiency, advanced computer skills in day-to-day tasks

• Excellent verbal and written communication in English 5.

Desirable Skills/Experience:

Advanced degree

Experience in all phases of a clinical study lifecycle

Basic knowledge of GXP outside of GCP (e.g., GMP)

Why AstraZeneca: Here you will join teams that unite clinicians, data scientists, statisticians and operational leaders around the same table to tackle complex disease with bold thinking and practical execution. We pair scientific curiosity with the power of data and technology to accelerate decisive studies, and we value kindness alongside ambition so you can take smart risks, learn fast and grow. With access to diverse modalities and programs across the pipeline, you will work on studies that matter, contribute to publications when great science comes alive, and build a long-term, meaningful career while making a measurable difference for patients worldwide.

Call to Action: Step into this role to shape pivotal global studies and amplify your impact—submit your application today and lead the next wave of clinical delivery!

Date Posted

Closing Date

AstraZeneca embraces diversity and equality of opportunity.  We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills.  We believe that the more inclusive we are, the better our work will be.  We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics.  We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.