Executive Director, Clinical Development – Immunology (MD)

Who We Are:

Neurocrine Biosciences is a leading biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering, developing and commercializing life-changing treatments for patients with under-addressed neurological, psychiatric, endocrine and immunological disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, hyperphagia in Prader-Willi syndrome, endometriosis* and uterine fibroids*, as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For more than three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. For more information, visit neurocrine.com, and follow the company on LinkedIn, X, Facebook and YouTube. (*in collaboration with AbbVie)

At Neurocrine, strong leadership drives both business results and team success. We look for leaders who think strategically, anticipate what’s ahead and set clear direction, while building and empowering high-performing teams. Successful leaders foster an environment where people are motivated to do their best work and deliver meaningful, measurable impact through sound decision-making and accountability.

About the Role:

We are seeking an accomplished physician drug development leader to help shape the future of our clinical development efforts in Immunology. As Executive Director, Clinical Development – Immunology, you will provide strategic medical and scientific leadership across the development of innovative therapies for immune-mediated diseases. Operating at the intersection of science, medicine, and drug development strategy, you will help define the direction of clinical programs, guide critical asset-level decisions, and influence development priorities across a growing and evolving portfolio.

Beyond clinical and therapeutic expertise, we are looking for a strategic leader who has successfully navigated the complexities of drug development, influenced high-impact decisions, and partnered across disciplines to advance programs through key clinical and regulatory milestones.

This is an opportunity to contribute beyond individual studies or programs, helping shape broader clinical development strategy, strengthen organizational capabilities, and ultimately bring meaningful new treatment options to patients.

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Your Contributions (include, but are not limited to):

Clinical Development & Asset Strategy

• Provide strategic medical and scientific leadership across immunology clinical development initiatives, supporting development direction at the indication, asset, and portfolio levels.
• Define and drive integrated clinical development strategies that balance scientific opportunity, patient needs, regulatory considerations, and organizational priorities.
• Lead high-impact development decisions, including indication selection and prioritization, clinical development pathways, study design, endpoint strategies, and benefit-risk assessments.
• Translate emerging scientific insights, clinical evidence, and competitive intelligence into actionable strategies that inform asset differentiation and long-term development opportunities.
• Guide clinical programs through critical development milestones, applying sound scientific judgment to complex clinical, regulatory, and business decisions.
• Partner with senior R&D leadership to evaluate development opportunities, assess program risks, and influence broader portfolio priorities and investment decisions.
• Anticipate evolving scientific, regulatory, and therapeutic landscapes to identify opportunities and proactively address development challenges.

Scientific & Medical Leadership

• Provide senior-level medical and scientific oversight across Phase I–IV clinical development activities, ensuring scientific rigor, patient safety, and alignment with program objectives.
• Direct the development and evaluation of clinical development plans, protocols, Investigator's Brochures, clinical study reports, and key regulatory submission materials.
• Lead the interpretation of clinical and translational data to inform development strategy, program progression, and critical decision-making.
• Provide strategic medical leadership for regulatory submissions and health authority interactions, including IND-related activities and other key development milestones.
• Partner with Clinical Operations, Translational Medicine, Regulatory Affairs, Biostatistics, Drug Safety, and other disciplines to integrate scientific and operational perspectives into cohesive development strategies.
• Maintain strong awareness of emerging scientific advances, treatment paradigms, and unmet medical needs across immunology and related therapeutic areas.

Cross-Functional & Organizational Influence

• Serve as a senior scientific and strategic advisor to clinical development teams and R&D leadership, influencing decisions across programs, functions, and organizational levels.
• Lead and contribute to multidisciplinary development teams, fostering alignment on scientific strategy, development priorities, and critical program decisions.
• Exercise independent judgment in navigating complex development challenges, balancing scientific rigor, development risk, and business considerations.
• Build and sustain relationships with key opinion leaders, clinical investigators, academic collaborators, and external scientific partners.
• Represent Neurocrine in scientific forums, investigator meetings, regulatory discussions, and external collaborations.
• Contribute to the evaluation of emerging therapeutic approaches and development opportunities that may inform the organization's broader scientific and portfolio strategy.

People & Organizational Leadership

• Provide scientific vision, strategic direction, and leadership to clinical development professionals and multidisciplinary teams.
• Lead, mentor, and develop talent, fostering a culture of scientific excellence, collaboration, accountability, and continuous learning.
• Influence and guide teams through complex decisions, organizational priorities, and evolving development needs.
• Partner with functional leadership to strengthen clinical development capabilities, optimize processes, and support long-term organizational effectiveness.
• Perform other duties as assigned.

Requirements:

Typical Experience, Education, Knowledge and Skills

• MD required and 6+ years of experience in clinical research and development (Phase I–IV) in either a pharmaceutical/biotechnology company and/or combination of clinical research/academic environment.
• Broad clinical and scientific expertise in immunology, immune-mediated diseases, or related therapeutic areas. Experience in rheumatology, dermatology, gastroenterology, or other areas of immunology is highly desirable.
• Demonstrated success in pharmaceutical or biotechnology clinical development, including experience shaping and advancing clinical development strategies across programs, assets, or indications.
• Strong understanding of drug development across Phase I–IV, including clinical trial design, regulatory strategy, clinical data interpretation, and development decision-making.
• Ability to integrate scientific, clinical, translational, and regulatory considerations into comprehensive development strategies.
• Strong knowledge of applicable regulatory requirements, clinical research standards, and the conduct of clinical studies.
• Experience contributing to regulatory submissions and interactions with health authorities.
• Demonstrated ability to operate as a strategic clinical development leader, influencing development direction beyond individual studies.
• Experience leading multidisciplinary development teams and driving complex clinical and scientific decisions.
• Strong business and scientific judgment, including the ability to evaluate development risks, identify opportunities, and influence strategic priorities.
• Ability to influence senior leadership and cross-functional stakeholders, including in matrixed environments without direct reporting authority.
• Exceptional scientific communication, presentation, and interpersonal skills, with the ability to translate complex clinical concepts into clear strategic recommendations.
• Ability to establish credibility and build trusted relationships with senior leaders, investigators, external experts, and multidisciplinary teams.
• Demonstrated effectiveness in driving alignment and influencing high-impact decisions across diverse stakeholders.

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Neurocrine Biosciences is an EEO/Disability/Vets employer.

We are committed to building a workplace of belonging, respect, and empowerment, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don’t line up to exactly what we have outlined in the job description.

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The annual base salary we reasonably expect to pay is $331,800.00-$452,000.00. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 35% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.