Clinical Research Nurse Practitioner

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Overview

The Nurse Practitioner will support the conduct of psychiatric clinical research studies by providing comprehensive clinical care and performing protocol-driven clinical activities. This role involves conducting structured psychiatric assessments, performing clinical evaluations across study visits, and completing study-related procedures, including phlebotomy and laboratory ordering. This role is integral to ensuring participant safety, protocol adherence, and the collection of high-quality clinical data.   The Nurse Practitioner will monitor participants receiving investigational interventions, including, but not limited to, ketamine, intranasal esketamine, psilocybin, and other emerging therapeutics for treatment-resistant depression throughout all phases of study participation. Responsibilities include ongoing clinical assessment, identification and documentation of changes in clinical status, and coordination with the study team regarding participant care and protocol requirements. This position integrates advanced clinical practice with research operations to support the accurate and reliable conduct of clinical trials. 

Required Skills and Abilities
1. Demonstrated knowledge of current principles, methods, and procedures for medical evaluation, diagnosis, and treatment. Possession of a CT APRN license (or eligibility) with ANA certification.
2. Ability to conduct informed consent procedures, support multidisciplinary clinical research projects, and participate in recruitment and assessment of study subjects. 
3. Strong clinical skills in patient assessment, care management, and prescribing for patient care related to research activities. 
4. Excellent communication and interpersonal skills for liaising with research team members, partners, and collaborators.
5. Organized and detail-oriented with the ability to function under pressure. Ability to maintain integrity in working with confidential information and make appropriate independent decisions.

Preferred Skills and Abilities

Master’s Degree from an accredited Advanced Nurse Practitioner program. 

Principal Responsibilities

 

1. Examines patients to collect information about their physical condition and establishes a clinical diagnosis. 2. Conducts physicals, provides treatment, formulates a health care plan and counsels patients on various health practices. 3. Encourages compliance with treatments plan through education, assessment of patient understanding and regular patient monitoring. 4. Provides reasonable and prudent medical care, practices appropriate management, and uses sound clinical judgment based on best practice standards and evidenced based medicine. 5. Obtains, compiles, and records patient medical data, including health history, progress notes and results of physical examination. 6. Provides preventive health practices to patients to maintain and improve health and prevent illness. 7. Coordinates patient care including ordering of laboratory tests and radiographic studies. 8. Interprets diagnostic test results for deviations from normal. 9. Prescribes therapy or medication as necessary. 10. May perform other duties as assigned. Required Education and Experience Master’s Degree from an accredited Advanced Nurse Practitioner program or graduation from a Physician Assistant (PA) Training Program accredited by the American Medical Association Council on Medical Education. Required License(s) or Certification(s) CT APRN license (or eligible) with ANA certification OR CT PA license (or eligible). Prescriptive privileges (or eligible) in the State of Connecticut, federal DEA license and CT DCP license for prescription of controlled substances. Physical Requirements While performing the duties of this job, the work involves sitting, standing, walking, bending, and occasional slight lifting. The employee occasionally lifts and/or moves up to 50 pounds when transferring a patient from chair or wheelchair to exam table and turning patients for examination. Proper body mechanics must be used when maneuvering patients.

Job Posting Date

08/25/2026

Job Category

Professional

Bargaining Unit

NON

Compensation Grade

Clinical & Research

Compensation Grade Profile

Nurse Practitioner (26)

Salary Range

$92,000.00 - $146,750.00

Time Type

Full time

Duration Type

Staff

Work Model

On-site

Background Check Requirements

All candidates for employment will be subject to pre-employment background screening for this position, which may include motor vehicle, DOT certification, drug testing and credit checks based on the position description and job requirements. All offers are contingent upon the successful completion of the background check. For additional information on the background check requirements and process visit "Learn about background checks" under the Applicant Support Resources section of Careers on the It's Your Yale website.

Health Requirements

This role is a healthcare worker position. Healthcare workers (HCW) are defined as university employees working a healthcare setting who have the potential for direct or indirect exposure to patients, human research subjects or infectious materials including body substance, contaminated medical supplies, devices and equipment, surfaces, or air.  HCW have specific health requirements that must be met prior to starting work, including MMR vaccine or immunity, varicella (chickenpox) vaccine or immunity, TB screening, COVID vaccine according to University policy, hepatitis B vaccine or immunity, and annual flu vaccination.

Posting Disclaimer

Salary offers are determined by a candidate’s qualifications, experience, skills, and education in relation to the position requirements, along with the role’s grade profile and current internal and external market conditions.

The intent of this job description is to provide a representative summary of the essential functions that will be required of the position and should not be construed as a declaration of specific duties and responsibilities of the position. Employees will be assigned specific job-related duties through  their hiring department.

The University is committed to basing judgments concerning the admission, education, and employment of individuals upon their qualifications and abilities and seeks to attract to its faculty, staff, and student body qualified persons from a broad range of backgrounds and perspectives. In accordance with this policy and as delineated by federal and Connecticut law, Yale does not discriminate in admissions, educational programs, or employment against any individual on account of that individual’s sex, sexual orientation, gender identity or expression, race, color, national or ethnic origin, religion, age, disability, status as a special disabled veteran, veteran of the Vietnam era or other covered veteran.

Inquiries concerning Yale's Policy Against Discrimination and Harassment may be referred to the Office of Institutional Equity and Accessibility (OIEA).

Note

Yale University is a tobacco-free campus.