Sr Manager, Biostatistics

We’re here for one reason and one reason only – to cure cancer. Every moment is dedicated to developing treatments and every action moves us one step closer to our goal. We’ve made incredible scientific breakthroughs and our pioneering personalized CAR T-cell therapies have changed the paradigm. But we're not finished yet.

Join Kite, as we make even bigger advances in cancer therapies, and help shape where our business and medical science goes next.

We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Kite and help create more tomorrows.

Job Description

We are seeking a highly motivated Senior Manager, Biostatistics, to provide statistical support and strategic input across clinical development, medical affairs, safety, and real-world evidence generation activities in support of Kite’s cell therapy portfolio.

The successful candidate will serve as a key statistical partner on cross-functional teams, contributing to the design, execution, analysis, interpretation, and communication of clinical and post-marketing studies in hematologic malignancies, solid tumors, and next-generation cell therapy programs. This role requires strong technical expertise in biostatistics, a collaborative mindset, and the ability to apply innovative statistical thinking to complex clinical and real-world data in a rapidly evolving oncology and cell therapy environment.

The Senior Manager will work closely with colleagues in Real-World Evidence, Statistical Programming, Clinical Operations, and Data Management, to support Clinical Development, Medical Affairs, Safety, Regulatory Affairs, Translational Medicine, and other functions to generate high-quality evidence that supports development strategy, regulatory submissions, scientific communication, and patient-centered decision-making.

Key Responsibilities

• Provide statistical leadership for clinical trials and related evidence-generation activities across Kite’s cell therapy programs, including CAR T and next-generation cellular therapies.

• Lead study design and analysis activities, including protocol development, endpoint selection, sample size determination, statistical analysis plans, interim analyses, ad hoc analyses and interpretation of results.

• Provide statistical support for regulatory submissions, health authority interactions, clinical study reports, and other key development documents.

• Contribute to scientific communications through publications, congress presentations, post-hoc analyses, and evidence-generation initiatives.

• Represent Biostatistics in governance and development forums, ensuring scientific rigor, regulatory compliance, and reproducibility across programs.

• Provide mentorship and technical guidance to junior team members and stay current with evolving regulatory guidance, statistical methodology, and advances in oncology and cell therapy.

Basic Qualifications

• PhD or PharmD

Preferred Qualifications

• Experience in hematology, oncology, immuno-oncology, cell therapy, gene therapy, or other advanced therapeutic modalities. Prior experience supporting CAR T-cell therapy or other immune-cell therapy programs is highly desirable.

• Knowledge of real-world data sources, registries, claims data, electronic health records, external control arms, or long-term follow-up evidence generation, including support of related scientific communications.

• Experience supporting regulatory submissions, health authority interactions, advisory committee preparation, or post-marketing commitments.

• Familiarity with advanced statistical methods such as Bayesian approaches, causal inference, adaptive designs, propensity score methods, multiple imputation and survival modeling etc.

• Ability to translate complex statistical analyses into clear business, clinical, regulatory, and scientific insights.

• Strong knowledge of statistical principles and clinical trial methodology in the pharmaceutical or biotechnology industry.

• Experience supporting clinical studies, external control arm and natural history studies from protocol development through analysis, reporting, and regulatory documentation.

• Solid understanding of oncology clinical development and hands-on experience on analyzing clinical trial data and real world data (including claims data, electronic health records, and external control arms, etc.). Proficiency in statistical programming using SAS and R.

• Strong communication and organizational skills, with the ability to explain quantitative findings, influence decision-making, and manage multiple priorities in a matrix environment.

People Leader Accountabilities:

• Create Inclusion - knowing the business value of diverse teams, modeling inclusion, and embedding the value of diversity in the way they manage their teams.

• Develop Talent - understand the skills, experience, aspirations and potential of their employees and coach them on current performance and future potential. They ensure employees are receiving the feedback and insight needed to grow, develop and realize their purpose.

• Empower Teams - connect the team to the organization by aligning goals, purpose, and organizational objectives, and holding them to account. They provide the support needed to remove barriers and connect their team to the broader ecosystem

 

The salary range for this position is: $169,320.00 - $219,120.00. Kite considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*.

For additional benefits information, visit:

https://www.gilead.com/careers/compensation-benefits-and-wellbeing

* Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.

Kite is a biopharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid, long-term durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered cell therapies designed to empower the immune system's ability to recognize and kill tumors. Kite is based in Santa Monica, CA. For more information on Kite, please visit www.kitepharma.com. Sign up to follow @KitePharma on Twitter at www.twitter.com/kitepharma.
 

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Kite Pharma is committed to providing equal employment opportunities to all employees and applicants for employment, and is dedicated to fostering an inclusive work environment comprised of diverse perspectives, backgrounds, and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, sex, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact [email protected] for assistance.

For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster.

NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT
YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT

Kite Pharma will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, (c) consistent with the  legal duty to furnish information; or (d) otherwise protected by law.
 

Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.

Kite Pharma provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.

For Current Kite Pharma Employees and Contractors:

Please apply via the Internal Career Opportunities portal in Workday.