Sr. Manager, Portfolio Operations

The Role 

The Portfolio Operations team at Moderna is responsible for management of the development portfolio from lead nomination to licensure. Moderna is seeking a motivated and energetic Sr Manager, Portfolio Operations to lead the execution, coordination, and continuous improvement of portfolio governance and senior leadership reporting processes across one or more operating units. The successful candidate will work closely with Program Management, Portfolio Analytics & Governance, Development leaders, Finance, Portfolio & Program Strategy, and other cross-functional stakeholders to ensure governance and reporting processes are clear, consistent, fit-for-purpose, and aligned with Moderna’s evolving operating model.

Here’s What You’ll Do  

• Lead Portfolio Operations activities for one or more operating units, including governance coordination, executive-level reporting, stakeholder alignment, and issue escalation.
• Identify and implement improvements to governance processes, templates, timelines, operating rhythms, decision tracking, stakeholder engagement, and change management approaches.
• Own coordination of the monthly clinical and development program update process for the Executive Committee, including input collection, synthesis of key messages, quality control, timeline management, and senior stakeholder alignment.
• Support preparation of quarterly Board update materials and memos by coordinating cross-functional inputs, shaping content, ensuring consistency of portfolio messaging, and highlighting key portfolio progress, decisions, risks, and upcoming milestones.
• Drive integration with Portfolio Analytics to embed fit-for-purpose portfolio reporting, dashboards, operational metrics, enrollment updates, data deliverables, and program goal tracking into governance and executive-level reporting processes.
• Build and maintain strong working relationships with Program Management, Development leaders, Portfolio Analytics & Governance, Finance, Clinical Development, Program Leads, Program Managers, and functional stakeholders to enable effective execution, escalation, decision support, and senior-level communication.
• Provide flexible support for emerging Portfolio Operations priorities as Moderna’s operating model, governance needs, and development portfolio continue to evolve.

Here’s What You’ll Need (Basic Qualifications)

• BS with 8-10+ years in biotech/pharma
• Advanced degree with 7-9+ years
• Significant experience in portfolio management, governance, or program strategy
• Demonstrated leadership of enterprise-wide initiatives
• PMP certification preferred
• Demonstrated experience building a governance function
• Experience in drug development, preclinical through clinical development
• Strong analytical skills, business knowledge and understanding of clinical development drivers. 
• Proven ability to analyze, develop and contribute to development of conceptual plans and lead implementation of process improvements and change initiatives across the organization. 
• Must be adept at working in a fluid environment and foster a strong collaborative spirit internally and externally. 
• Strong personal skills to influence without authority within a highly technical environment, motivate others and manage conflict. 
• Demonstrated experience interacting with senior and executive leadership. 
• Strong written and oral communication skills as well as demonstrated organizational aptitude. 

Pay & Benefits

At Moderna, we believe that when you feel your best, you can do your best work. That’s why our benefits and well-being resources are designed to support you—at work, at home, and everywhere in between.

• Competitive healthcare, plus voluntary benefit programs to support your unique needs
• A holistic approach to well-being, with access to fitness, mindfulness, and mental health support
• Family planning benefits, including fertility, adoption, and surrogacy support
• Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
• Savings and investments to help you plan for the future
• Location-specific perks and extras

The salary range for this role is $130,800.00 - $209,400.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An individual’s position within the salary range will be based on several factors including, but not limited to, specific competencies, relevant education, qualifications, certifications, experience, skills, performance, and business or organizational needs. The successful candidate may be eligible for an annual discretionary bonus, other incentive compensation, or equity award, subject to company plan eligibility criteria and individual performance.

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.  

By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities. 

We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. 

If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities. 

Our Working Model 

As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact. 

Moderna is a smoke-free, alcohol-free, and drug-free work environment. 

Equal Opportunities

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law.  Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!

Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements. 

Accommodations

We’re focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best. 

Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at [email protected]. 

Export Control Notice This position may involve access to technology or data that is subject to U.S. export control laws, including the Export Administration Regulations (EAR). As such, employment is contingent upon the applicant’s ability to access export-controlled information in accordance with U.S. law. Due to the nature of the work and regulatory requirements, only individuals who qualify as U.S. persons (citizens, permanent residents, asylees, or refugees) are eligible for this position. For this role Moderna is unable to sponsor non-U.S. persons to apply for an export control license. #LI-NH1

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