Operational Technology and Manufacturing Manager

We manufacture and supply reliable, high-quality medicines and vaccines to meet patients’ needs and drive our performance.
Our network of 37 medicines and vaccines manufacturing sites delivered 1.7 billion packs of medicines and 409 million vaccine doses in 2024 to help make a positive impact on the health of millions of people. Our supply chain is not just core to our operations; it’s vital to bringing our innovations to patients as quickly, efficiently and effectively as possible. Technology is transforming how we manufacture medicines and vaccines, enabling us to increase the speed, quality and scale of product supply.
We need the very best minds and capability to help us on our journey to make more complex products, harnessing the power of smart manufacturing technologies including robotics, digital solutions and artificial intelligence to deliver for patients.

Job title: Operational Technology and Manufacturing Manager

Location: Rosia, Italy

Employment type: Permanent

Closing date for applications: 6 August 2026

Position Summary

The OT Security and System Architecture Manager – OT Strategy, Resilience and Architecture role is accountable for defining, governing, and continuously improving the OT cybersecurity strategy, resilience framework, and target architecture for the site. The role ensures that OT systems are secure, resilient, compliant, and architecturally sound by design, GMP/GxP compliance, data integrity, and long‑term digital transformation objectives. Acting as the architectural and security authority for OT, the role bridges Automation, OT Operations, IT, Quality, and Global Cybersecurity, translating standards and threat landscapes into practical, risk‑based, and sustainable OT architectures.

This is an individual contributor role (no direct reports).

Responsibilities

• OT Security Strategy:
  • Define and maintain the Site OT Security and Strategy, aligned with Global OT Cybersecurity policies and Site Master Plan. Embed security‑by‑design and resilience‑by‑design principles into OT systems, networks, and execution platforms.
  • Identify and manage cyber, operational, and architectural risks impacting OT systems and manufacturing continuity.
  • Lead site‑level OT risk assessments, threat modelling, and mitigation plans.
• OT Architecture Governance
  • Define and govern the Target OT Architecture (zones, conduits, network segmentation, remote access, edge and execution layers).
  • Ensure consistency and compliance of OT solutions (PLC, SCADA, DCS, MES, LES, historians, data platforms) with approved OT architectures.
  • Review and approve OT architecture designs for: New projects, Major changes, Technology refresh and obsolescence programs
  • Maintain architectural documentation (OT LDD, HLD, reference architectures).
• Lifecycle, Obsolescence & Technology Evolution
  • Drive secure OT lifecycle management, from design to decommissioning.
  • Support OT obsolescence management plans ensuring security, resilience, and compliance are preserved.
  • Evaluate emerging OT security and architecture technologies, supporting informed investment decisions.
• Governance, Compliance & Stakeholder Engagement
  • Ensure OT architectures meet GMP/GxP, Data Integrity (ALCOA+), CSV and cybersecurity requirements.
  • SPOC for Business continuity delivering look ahead systems/services down time plan
  • Act as Subject Matter Expert (SME) for OT security and architecture during audits and inspections.Partner with Automation, Digital, Quality, IT, MSAT, and Global functions to align priorities and execution.
  • Promote OT security awareness and architectural discipline across the site.

Why you?

Qualifications & Skills

We are looking for professionals with these required skills to achieve our goals:

• Master’s degree in Engineering (Automation, IT, Electronics, Industrial, or equivalent).

• At least 10 years of experience in similar roles in Pharma companies.

• Proven leadership experience in Automation, Digital, or OT roles within complex and regulated industrial environments.

• Fluent Italian and English (written and spoken).

Additional Skills

• OT architectures and industrial security concepts (zones & conduits, defense‑in‑depth).

• Industrial automation systems (PLC, SCADA, DCS, MES/LES).

• OT cybersecurity principles, threat landscape, and mitigation strategies.

• GMP/GxP regulated environments, CSV, and Data Integrity.

• Network segmentation, secure remote access, and industrial protocols.

• Risk management and resilience frameworks.

• Degree in Automation, Electrical, Electronic, Computer Engineering or equivalent.

• Proven experience in OT security, system and cloud architectures, or industrial cybersecurity within regulated manufacturing environments.

• Experience working in matrix organisations with global and local stakeholders.

What we offer:

• Permanent contract in a very Inclusive environment

• Smart Working up to 50%

• Flexible Benefits

• Company Healthcare Plan

• Integrative pension fund

• Employee Assistance Programme

• Prevention services and vaccination clinic

• Tax assistance

• Local nursery agreement

• Postal service, laundry, shoe repair and tailoring

• On site canteens and coffee corners

• Free company bikes and shuttle

Please note that relocation support cannot be provided; therefore, only candidates who are already based in the indicated country can be considered.

Please take a copy of the Job Description, as this will not be available post closure of the advert. 
When applying for this role, please use the ‘cover letter’ of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.

Skills

Data Integrity, Digital Fluency, GxP Regulations, Manufacturing Technologies, Pharmaceutical Manufacturing, Problem Solving, Risk Awareness, Standards Compliance

 

 

Italian Salary Range / Fascia retributiva in Italia: EUR 47,325 to EUR 78,875The annual gross base salary range for new hires in this position is listed above for each applicable location. These ranges take into account a number of factors including the candidate’s skills, experience, education level and the market rate for the role. In addition, this position may offer an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. More detailed information on the total benefits package will be supplied during the recruitment process. This role is available for applicants from multiple locations, and therefore salary ranges for certain locations are also shown. Salary ranges for other locations are shown because some markets have pay transparency laws that require salary information on job postings, and those locations are potential job sites for this role. If salary ranges are not displayed in the job posting for a specific location or country, the relevant compensation will be discussed during the recruitment process. Please note salaries vary by country based on the candidate’s skills, experience, education level and the market rate for the role. Offers are typically made within the advertised range based on the candidate’s skills, experience and qualifications, with the upper end generally reserved for highly experienced candidates or other exceptional circumstances aligned with these criteria.La fascia salariale della Retribuzione Annua Lorda (RAL) per i nuovi assunti in questa posizione è indicata sopra per ciascuna sede applicabile. Queste fasce tengono conto di diversi fattori, tra cui le competenze, l'esperienza, il livello di istruzione del candidato e le condizioni di mercato per il ruolo. Inoltre, questa posizione potrebbe prevedere un bonus annuale e la partecipazione al nostro programma di incentivazione a lungo termine basato sull’assegnazione azioni, in funzione del livello del ruolo. Informazioni più dettagliate sull’intero pacchetto retributivo e sui benefit saranno fornite durante il processo di selezione. Questo ruolo è aperto a candidati basati in diversi paesi; per tale motivo sono indicate le fasce retributive relative a ciascun paese. La pubblicazione di tali fasce, per altri paesi, che sono possibili sedi lavorative per questa posizione, risponde a normative locali in materia di trasparenza retributiva, che richiedono l’indicazione delle retribuzioni negli annunci di lavoro. Qualora per una specifica sede o paese non sia indicata una fascia retributiva, le relative condizioni economiche saranno discusse nel corso del processo di selezione. E’ importante considerare che le retribuzioni variano da paese a paese in base alle competenze, all’esperienza, al livello di istruzione del candidato e alle condizioni di mercato per il ruolo. Le offerte vengono generalmente formulate all’interno della fascia indicata, tenendo conto delle competenze, dell’esperienza e delle qualifiche del candidato; il limite superiore è di norma riservato a candidati con un’esperienza particolarmente consolidata o a circostanze eccezionali coerenti con tali criteri.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

Should you require any specific adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on [email protected].

Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

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