Process Development Research Scientist

Site: The General Hospital Corporation

 

Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

 

Job Summary

In consultation with their Principal Investigator (PI), undertake and execute a program of scientific study culminating in publication. Drives research projects scientifically and determines the course of research as evidenced by leadership, obtaining funding, writing, or other recognition. May not necessarily receive independent resources; however, their contribution is essential to the conceptual/scientific success of the project. They assist their PI in the training and supervision of other laboratory personnel and in a wide variety of administrative tasks, as necessary.

Does this position require Patient Care? No

Essential Functions
-Makes proficient intellectual contributions to scientific strategies of the group/lab and plays a leadership role by acting as subject matter authority in the field.

-Contributes to the design and execution of experiments and/or research projects.

-Exercises judgment in selecting methods and technologies to obtain results.

-May collaborate with external researchers and/or receive external project funding support.

-Presents results and prepares publications.

-May assist PI in the training and supervision of other staff.

 

 

The Massachusetts General Hospital Cancer Center’s Process Development Laboratory seeks a full-time Process Development Scientist I to support and advance its translational cell and gene therapy research platform. The Process Development Laboratory is a highly integrated, innovation-driven facility dedicated to translating next-generation cellular immunotherapy and gene engineering technologies into clinically deployable manufacturing solutions. This position offers an exceptional opportunity for an independent and motivated scientist to serve as a scientific lead within a multidisciplinary translational team, working at the interface of biology, engineering, manufacturing science, and regulatory strategy.

The successful candidate will contribute to the design, development, optimization, and clinical translation of novel manufacturing workflows poised for IND-enabling studies and early-phase clinical trials, while operating in a collaborative academic medical center environment.

Preferred Qualifications:

· Demonstrated experience in cell and/or gene therapy research and process development.

· Hands-on experience working with primary human cells, preferably immune effector cells.

· Strong foundation in cell culture, molecular biology, and translational experimental design.

· Experience with CAR T-cell or immune effector cell manufacturing.

· Familiarity with CRISPR/Cas-based genome editing technologies.

· Experience with viral vector production or gene delivery platforms.

· Exposure to cGMP environments, IND-enabling studies, or regulated manufacturing settings.

· Experience with closed-system or automated manufacturing platforms.

· Prior experience contributing to regulatory documentation, technology transfer, or validation activities.

The salary range for this position is $60,000.00 to $96,000.00 annually. At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience, if applicable, education, certifications, and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package.

In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums, and bonuses as applicable, and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.
 

 

Onsite

 

149 Thirteenth Street Building 149

 

40

 

Regular

 

Day (United States of America)

 

1200 The General Hospital Corporation is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.

 

Mass General Brigham Competency Framework