- Location
- South Africa, Johannesburg
- Workplace
- Onsite
- Type
- Full-time
- Department
- Healthcare
- Seniority
- Entry
- Experience
- 4+ years
- Visa
- Not sponsored
- Source
- Workday
Description
ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.
As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.
As a Senior Clinical Research Associate at ICON, you will be responsible for the monitoring and oversight of clinical trial sites, ensuring studies are conducted in accordance with the protocol, ICH‑GCP, and applicable local and international regulatory requirements.
This role sits within ICON Strategic Solutions, embedded with a sponsor partner, offering the opportunity to build strong site relationships while delivering high‑quality clinical research.
What You Will Do:
In this role, you will be responsible for the end‑to‑end monitoring and oversight of investigator sites across the full clinical trial lifecycle.
Key responsibilities include:
- Conduct site qualification, initiation, monitoring, and close‑out visits in line with the Clinical Monitoring Plan
- Maintain full ownership of assigned investigator sites, ensuring effective management through to study close‑out
- Ensure investigator site compliance with study protocols, ICH‑GCP, sponsor SOPs, and regulatory requirements
- Provide initial and ongoing training to site personnel on protocol requirements, procedures, and Good Clinical Practice
- Support study start‑up activities, including feasibility, essential document collection and review, and Ethics Committee submissions
- Identify site‑level risks and issues, and support the implementation of corrective and preventive actions
- Build and maintain effective, collaborative working relationships with investigators, site staff, and cross‑functional study teams
Your Profile:
To succeed in this role, you will bring strong clinical monitoring experience, independence in site management, and a proactive approach to quality and compliance.
Required qualifications and experience:
- A degree in life sciences, nursing, or a related discipline
- Proven experience working as a Clinical Research Associate, with at least 4 years’ independent site monitoring experience in a CRO or pharmaceutical environment
- Strong working knowledge of ICH‑GCP guidelines and applicable local and international regulatory requirements
- Ability to manage multiple investigator sites and priorities independently while meeting tight deadlines
- Willingness to travel up to 60% of the time and possession of a valid driving licence
- Based in Gauteng, South Africa
- Cardiovascular therapeutic area experience is desirable
Employment with ICON is contingent upon having the legal right to work in the country where the role is based.
Rewards & Benefits
ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.
Benefits may include:
- Competitive base salary and performance related incentives
- Health and wellbeing programmes including medical, dental, and vision coverage where applicable
- Retirement and pension plans
- Life assurance and disability coverage
- Employee assistance programmes and wellbeing resources
- Learning and development opportunities through structured training and career pathways
Benefits may vary depending on role and location.
Visit our careers site to read more about the benefits ICON offers.
Inclusion and Accessibility
ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.
If you require reasonable accommodations during the recruitment process, please let us know or submit a request here.
Are you a current ICON Employee? Please click here to apply
