Senior/Principal Scientist - NMR Expert

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The Position

NMR Expert in pRED-pCMC Analytical Chemistry

In Roche’s Pharmaceutical Research and Early Development organization (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicine. Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.

This role is situated within the preclinical Chemistry, Manufacturing, and Controls (pCMC) department, part of the Small Molecule Research organization in pRED Therapeutic Modalities (TMo). We pave the path for drug candidates from early research to development in a diverse, ambitious, and innovative environment. Collaborating actively with our discovery and development partners, we leverage cutting-edge technologies and scientific excellence to transform molecules into future medicines. As CMC experts, we bring a rich diversity of technical expertise in chemistry, formulation design, material science, and analytical chemistry, pioneering advancements in small molecules, peptides, and nucleic acid-based medicines.

The Opportunity

We are offering a unique opportunity for a hands-on NMR Expert in our Analytical Molecular Characterization group. As a Centre of Excellence for Analytics, we provide state-of-the-art methods and services for determining chemical structures, purities, and impurities, supporting portfolio projects throughout the entire value chain. In this role you plan, run and report NMR experiments for structure elucidation and inter- and intra-molecular interaction studies.

• Innovative Analytics: By applying cutting-edge analytics you support synthesis and formulation development enabling fast progress for projects, and identification of possible challenges.

• Method Development: You develop and implement new NMR experiments and give input for future developments of our NMR group.

• Scientific Excellence: You enhance scientific excellence by identifying relevant industry trends, and building and maintaining academic partnerships. 

• Strategic Vision: You contribute deep scientific insights to shape the mid- and long-term strategy for NMR within the Roche portfolio. Working alongside the NMR group and the Leadership Team, you guide the translation of your strategic input into actionable team strategies. 

• Collaboration and Relationship Building: You foster trustful relationships and effective collaboration with internal discovery and technical development teams as well as with external partners.

Who You Are

• Educational Background: Masters with a minimum of 5 years or PhD in analytical chemistry or related fields with a minimum of 3 years of professional experience in the industry.

• Technical Expertise: Comprehensive knowledge of NMR analytics and its applications paired with a deep understanding of the technical and theoretical basis beyond the standard experiments for liquid and solid state NMR. Experience with other methods for biophysical characterization is a plus.

• Proven Experience: Hands on expertise in structure elucidation and interaction studies by NMR for synthetic oligonucleotides and/or peptides. Demonstrated expertise on higher order structure studies and aggregation studies.

• Mindset: You possess an open-minded and highly proactive, "just-do-it" approach. You enjoy problem-solving and developing new ways of working. You comfortably navigate working in a multidisciplinary matrix team.

If you are an expert in NMR and enjoy being a part of an innovative and impact oriented team, we would love to hear from you.

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.

Roche is an Equal Opportunity Employer.