Crescent Biopharma’s vision is to build a world leading oncology company bringing the next wave of therapies for cancer patients. The Company’s clinical-stage pipeline includes its lead program, a PD-1 x VEGF bispecific antibody, as well as novel antibody-drug conjugates. By leveraging multiple modalities and established targets, Crescent aims to rapidly advance potentially transformative therapies as single agents and as part of combination regimens to treat a range of solid tumors. For more information, visit and follow the Company on and
We are seeking an experienced Senior Director, Quality Control to join as a key leader within Crescent's Quality organization, responsible for providing strategic and hands-on Quality Control leadership across company’s biologics and ADC programs, and future pipeline growth. Partnering closely with Analytical Sciences, GMP Quality Assurance, CMC/Technical Operations, Supply Chain, and Regulatory Affairs, you will provide phase-appropriate QC oversight from early development through late-stage development and commercialization within a global outsourced testing and manufacturing network. You will ensure reliable release and stability testing while building the QC infrastructure, laboratory network, and operating controls needed to advance programs into Phase 3, PPQ, BLA/MAA submission, and commercial readiness.
Crescent's operating model requires clear, collaborative accountability between Analytical Sciences and QC. Analytical Sciences leads analytical development and performs the primary technical work through method development, characterization, qualification, validation strategy, and PPQ readiness. QC provides oversight and operational input during early development, assumes increasing responsibility for method transfer, validation execution oversight, laboratory readiness, and GMP testing as programs mature, and takes primary ownership of routine QC operations and analytical method lifecycle management following transition to late-stage and commercial operations.
Success in this role requires a collaborative, hands-on leader who understands both analytical development and commercial QC operations, can establish effective governance across internal and external partners, and thrives in a fast-paced biotechnology environment while balancing scientific rigor, compliance, speed, and pragmatism.