Commercial Business Director, Advanced Specialty Care, West Region

Commercial Business Director, Advanced Specialty Care, Epithelial Biologics Franchise

At AstraZeneca we turn ideas into life-changing medicines. Working here means thinking big and working together to make the impossible a reality. We’re focused on the potential of science to address the unmet needs of patients around the world. We commit to those areas where we think we can really change the course of medicine and bring big new ideas to life.

At AstraZeneca, we are taking bold action on climate because we recognize the connection between healthy people and a healthy planet. As part of our flagship Ambition Zero Carbon program, we have committed to a fully electric vehicle (EV) fleet by the end of 2025, which means that all of our drivers will be assigned an EV.

As a Commercial Business Director for the Epithelial Biologics Franchise Advanced Specialty Care Team, you’ll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients’ lives!

This Commercial Business Director serves as a regional second-line leader for our growing, multi-indication TSLP Franchise, with responsibility for a large organization of District Sales Managers and their sales representatives. The role is accountable for building a high-performance culture, driving competitive business results, and accelerating professional development across the organization while leading the total business within a broad geography spanning independent practitioners, health systems, and alternative sites of care across Pulmonology, Allergy, and Otolaryngology. The Commercial Business Director will establish trusted relationships with key customers and advocates who can influence patient care and advance the business. Key lifecycle priorities include maximizing performance in the established Severe Uncontrolled Asthma (SUA) indication, accelerating growth of the newly launched Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) indication, and preparing the organization for a potential, exciting future launch within the Gastroenterology specialty.

Main Duties and Responsibilities

• Well-rounded understanding of disease states and treatment pathways and innovative therapies prevalent in Advanced Specialty Care settings and varied healthcare environment, and able to influence specialists and multi-disciplinary stakeholders.

• Expertise in leveraging analytical objectivity, and complex data and insights to focus on prescribing patterns to optimize account strategies and prioritize high-value accounts for highly specialized markets.
• Drives a targeted approach in account planning and execution.

• Demonstrates resilience and adaptative leadership while driving performance in complex and ambiguous Advanced Specialty Care market environment and effective execution of Brand strategies

• Ensure sales forecasts and operational budgets are met or exceeded within the therapeutic area at a regional level.

• Model and coach to AZ’s Leadership capabilities by creating significant impact, climate of trust and influence over the stakeholders across specialty care environments and external networks.​

• Fosters a Growth Mindset, and continuous learning and improvement. Leverages new technology and data insights to capitalize on opportunities that improves patient care and streamlines process efficiency.

• Inspires a culture of entrepreneurial thinking and transformative patient-centric practices that embraces curiosity, ownership, accountability and engagement within the entire team through mentoring, coaching and continuous feedforward.

Essential Requirements

• Bachelor’s Degree

• 8+ yrs of demonstrated Sales or Commercial experience or a combination of: pharmaceutical, healthcare, scientific, clinical, institutional or related industry.
• 5+ yrs proven leadership capabilities and/or people management experience
• A valid driver’s license and safe driving record

Essential Skills and Capabilities

• Clinical Acumen
• Strategic Business Planning
• Drives Performance & Agility
• Enterprise Leadership
• Growth and Innovation Mindset

Desirable Attributes and Experiences

• Advanced degree in business administration, leadership, or a related field.
• Specialty healthcare experience, including account management and complex reimbursement models.
• Track record of competitive performance across the biologics prescription journey in Pulmonology, Allergy, Otolaryngology, and/or Gastroenterology.
• Broad commercial or leadership experience with demonstrated impact within and beyond the sales function.
• Proven ability to build culture and followership while developing team business acumen and commercial capabilities.
• Confident enterprise influencer who constructively challenges, supports, and defends decisions at all organizational levels.
• Recognized strong collaborator with stakeholders internal and external to the organization.
• Demonstrated aspiration and potential for broader commercial leadership and organizational impact.

The annual base pay for this position ranges from $ 233,464.00 - 350,196.00 USD. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

Date Posted

29-Sept-2026

Closing Date

04-Oct-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.