Clinical Laboratory Scientist

Description

We are seeking a highly motivated and skilled licensed CLS to join our team. The ideal candidate will have experience in running Next Generation Sequencing (NGS) and knowledge of molecular biology techniques.

Essential Responsibilities:

• Ensure that the equipment is calibrated, maintained, and operated according to the manufacturer's guidelines and standard operating procedures.
• Adheres to the CAP, CLIA and NYS regulations.
• Run protocols for sample collection, processing, storage, and tracking in LIMs to ensure the integrity and traceability of the samples throughout the NGS workflow.
• Run clinical and R&D samples for NGS and molecular biology techniques, including microdissection, FFPE nucleic acid extraction, NGS library preparation, sequencing, data analysis, and quality control measures with appropriate NGS controls.
• Perform and train other CLS’s on established NGS and molecular biology procedures, including macrodissection, FFPE nucleic acid extraction, NGS library preparation, sequencing, and data analysis, including quality control measures.
• Perform validation testing to ensure with selected reagents and controls to ensure the assay meets the required performance specifications.
• Perform validation studies to assess the performance characteristics of the NGS assay, including sensitivity, specificity, accuracy, precision, and reproducibility.
• Analyze and interpret data using appropriate statistical methods and software, including sensitivity, specificity, accuracy, precision and reproducibility.
• Maintain accurate records and documentation of experiments and results.

Requirements

• Minimum 4 years as a certified or licensed clinical laboratory scientist
• California Clinical Laboratory Scientist (Highly Preferred: California Clinical Genetic Molecular Biologist Scientist license - CGMBS.)
• Must be well-organized, open-minded, decisive, and flexible. They must be able to communicate well with others, and work as a team. Good writing skills and and extensive computer experience are necessary
• Experience with Macrodissection, RNA extraction and downstream analysis
• Strong experience in development of targeted library, conducting sequencing NGS library preparation, sequencing, and data analysis
• Experience in project management and organization
• Excellent record-keeping and documentation skills
• Strong communication skills and ability to work in a team-oriented environment
• Validation and SOP writing experience a plus
• Must have superior work ethic, driven and be results oriented
• Comfortable in a fast-paced environment
• Excellent oral and written communication skills
• Preferred Bachelor's or Master's degree in Molecular Biology, Biochemistry, or related field
• Anatomic or Clinical Pathology experience
• Prior experience with NextGen sequencing instruments.
• Minimum of 4 years of molecular and histology experience within an anatomic pathology laboratory or clinical laboratory.