- Salary
- $220k – $250k/yr
- Location
- Emeryville, CA
- Workplace
- Onsite
- Department
- 4:59 Initiative
- Seniority
- Director
- Experience
- 10+ years
- Education
- PhD
- Source
- Lever
Description
THE COMPANY
Prolynx is a preclinical biotechnology company with a vision to become the industry leader in ultra-long-acting medicines that improve outcomes for patients with obesity, cardiometabolic, and other diseases. The company is developing a next-generation portfolio of incretin and non-incretin therapeutics designed for once-monthly and once-quarterly dosing. Its proprietary, first-in-category platform uses a hydrogel-based microsphere technology with independently tunable release-linker chemistry to enable highly predictable pharmacokinetics and sustained drug exposure. Prolynx is backed by leading investors including 5AM Ventures, OrbiMed, and Monograph Capital and is based in Emeryville, CA.
Join a multidisciplinary team of talented scientists developing innovative and differentiated medicines - where we pursue purposeful science and let data and patient needs drive decisions. Prolynx provides an environment where you work, learn, and grow alongside experienced drug developers, inventive scientists, and business professionals. Bring your passion, creativity, and energy to our mission. At Prolynx, contributions are valued regardless of title, people are trusted to own their area of expertise, and teammates readily step in to help one another. We share what we know and succeed together. If that sounds like the place for you, we’d like to meet you.
THE ROLE
We are seeking an experienced leader in toxicology to build and direct nonclinical safety strategy as Prolynx advances its ultra-long-acting, hydrogel-based conjugate therapeutics toward and through the clinic. You will lead the toxicology function and address needs across the portfolio, addressing systemic safety of peptide payloads, and you serving as the primary nonclinical safety voice on program teams, with regulatory agencies, and with senior leadership.
Prolynx has an efficient, outsourced model for nonclinical safety. You will lead a global network of toxicology CROs and work hand in hand with expert nonclinical consulting partners to design, execute, and monitor critical studies. You will author reports and regulatory documents, ensure that all studies are designed well, conducted to GLP standards, and accepted by regulators. As a member of the Preclinical Leadership Team, you will serve as a senior scientific voice shaping program strategy, resourcing and go/no-go decisions alongside the Chief Scientific Officer and other functional leaders.