Senior Scientist - Critical Reagent Management

Job Description Summary

If you are curious, scientifically minded, and want to positively impact society by speeding delivery of novel therapies to patients, then look no further, Novartis Biomedical Research is the place to be. As a Senior Scientist - Critical Reagent Management in the Translational Medicine PK Sciences Bioanalytical group, you will have the opportunity to make a difference. If you have a collaborative nature, a commitment to teamwork across an organization and a relentless focus on improving patient care we want you to apply.

In this role, you will be part of the Critical Reagents team, coordinating the production and inventory management of biological reference standards and critical reagents used in internal and external bioanalytical laboratories. The position requires a strong scientific and laboratory background and project management skills with a focus on critical reagent production, handling, storage, management, and a customer service mindset. You will work with an elite team of scientists involved in the development and qualification of small and large molecule assays supporting pharmacokinetic, pharmacodynamic and immunogenicity studies across all phases of the drug discovery & development pipeline.

 

Job Description

 Major Responsibilities

• Contribute to the design strategies and production platforms to meet the team needs for the outsourced production of critical reagents from both Novartis Biologics database and in-licensing programs.
• Apply scientific expertise, strong organization and documentation skills to the outsourced productions of customized critical reagents, by contributing to the production strategy, identifying and reviewing production protocols, requesting quotes, interacting with vendors, requesting funds, collecting and providing updates to stakeholders on production timelines.
• Identify protocols for cloning, expression, purification and requalification of in-house monoclonal antibodies, recombinant proteins, Stable Isotope Labelled (SIL) proteins in different hosts (Escherichia coli, yeast, insect, mammalian cell cultures and hybridoma cultures).
• Provide scientific expertise and utilize strong collaboration skills to work with colleagues from various departments, stakeholders and external service providers to optimize processes and inventory management systems to meet the needs for outsourced production.
• Provide technical and process troubleshooting and find suitable resolutions.
• Maintain up-to-date documentation, including documentation storage and archiving. Prepare technical documentation as required.
• Provide instruction and technical training to other scientific staff if needed, contributing to team growth

Essential Requirements

• MSc or PhD / Pharm.D. level scientist with appropriate experience in a relevant field.
• 4+ years in the pharmaceutical industry.
• Experience in working in a drug discovery or development or relevant experience in a CRO, Pharma or Biotech highly desirable.
• Experience in working with cross-functional teams in a highly dynamic, matrixed, project-team environment.
• Strong project management, critical thinking, and problem-solving skills.
• Strong oral and written communication skills.
• Ability to work independently with minimal supervision on assigned tasks.
• Experience in planning, launching, and tracking outsourced production of customized reagents.
• Experience in reagent inventory management.
• Experience in SharePoint Site maintenance. Previous hands-on experience creating solutions using KNIME and Spotfire will be an added value.
• Experience in production of monoclonal antibodies, recombinant proteins, Stable Isotope Labelled (SIL) proteins in different hosts (Escherichia coli, yeast, insect, and mammalian cell cultures or hybridoma cultures), including cloning, upstream and downstream processes in biopharmaceutical environment

 

Skills Desired

Adobe Photoshop, Chemistry, Collaboration, Curious Mindset, Drug Development, Employee Recruitment, Oscilloscope, Patient Care, Sales, Teamwork